The Science and Business of Biotechnology

<div class="xblock xblock-public_view xblock-public_view-vertical" data-runtime-class="LmsRuntime" data-block-type="vertical" data-usage-id="block-v1:MITx+15.480x+3T2021+type@vertical+block@4e8853fab13e4e018d2194ee4e47e61f" data-course-id="course-v1:MITx+15.480x+3T2021" data-init="VerticalStudentView" data-has-score="False" data-graded="False" data-request-token="21d032bf5fe411f0bb5812a532d12aaf" data-runtime-version="1"> <h2 class="hd hd-2 unit-title">Why is Medicine Different?</h2> <div class="vert-mod"> <div class="vert vert-0" data-id="block-v1:MITx+15.480x+3T2021+type@video+block@473a0a58f42a405586e5a8259920584c"> <div class="xblock xblock-public_view xblock-public_view-video xmodule_display xmodule_VideoBlock" data-runtime-class="LmsRuntime" data-block-type="video" data-usage-id="block-v1:MITx+15.480x+3T2021+type@video+block@473a0a58f42a405586e5a8259920584c" data-course-id="course-v1:MITx+15.480x+3T2021" data-init="XBlockToXModuleShim" data-has-score="False" data-graded="False" data-request-token="21d032bf5fe411f0bb5812a532d12aaf" data-runtime-version="1"> <script type="json/xblock-args" class="xblock-json-init-args"> {"xmodule-type": "Video"} </script> <h3 class="hd hd-2">Why is Medicine Different?</h3> <div id="video_473a0a58f42a405586e5a8259920584c" class="video closed" data-metadata='{"speed": null, "ytMetadataEndpoint": "", "recordedYoutubeIsAvailable": true, "captionDataDir": null, "autoAdvance": false, "poster": "https://mitx-edx-video-meta-storage.s3.amazonaws.com/media/video-images/58a4bbdfa2254364a34fb032d586853e.png?Signature=zfeRPCBTpUHdST1L77f3qCnExsc%3D&AWSAccessKeyId=ASIA4QDFFSUR7AJWXVI4&x-amz-security-token=IQoJb3JpZ2luX2VjEP3%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEaCXVzLWVhc3QtMSJIMEYCIQDrL6n%2B6JZK2mP55A%2BuycKvWm%2Bu7QSkQfWE8Ca5X54KWwIhAL3SiAgLUuHMBLLvzN%2FZs5VmdQ3FIcWxprkcUoY%2B5V%2BoKroFCBUQBBoMODU5MjA1NjM3NDExIgwadLjPSqqzBrk%2B3QAqlwUR5uIAm4pfv2QpR97GfxL%2F%2B5Nvv2cTm%2FsbjYl11S8%2Bpn2Jj5GvOCaoCc6RrUrBezUuKFKY5sQzNBeReNVA72oTx5CKUfBeVeg%2FyjgMf43RmXtsadbPsi1LgluiwVna9Zxe%2Ft7U5Zm2UUO7oMTrr7G3ashtWD8DwPyTpVfNmRkFBPwSY%2FG3QDpnvrqm0JwTh7FBdZSM6oZR5k7vUG8MSqDd8RuL9f%2BjUspEAcTGuk6vtQqA8b0%2BtMnIlxfMWkZ2%2BlWIL2%2F2F%2FhafgEALddld3jCrJ7UIAxKTcD2B5ZI%2BzZGpzYh9cVSKHaGOdXNTVNKO4z1ViayQccZUyH1G6%2Bsx9pq3WOotc85sp5PzJfmu5WitZ4Rd31Yj0Grf7q581FvJdi7Penmyf071jQne1kLJvyf%2BtKeyQXMSViZYR%2BypAaFxzbJF61q33XvFO1wABmpGkXL14S5sU5DTyyl6AJU%2FQ1zrOzxF2cRGFuJtxUX70fsil8aNNI85kglBLZMLBiYEiA%2FQ50MNoQS9ITns4CMLEjbZPu8rRPw2DGSlPsEuOgv7PBqgsOEMiJSxQNLx8InyR5YUYKMW%2BW1bClZxoAwbmN0zb39xi8ZINq2zQ2Gj94AELxWbwNIJq2ZBfZMXD5AT8QDvMJpZj0ANQDuMkX4tNDvVkhUNRDxJgsiQoMDULNUaVsRdUUOp1yWJXjZ8yEVYWWzwLJ%2BymU5QhE%2FNWkoGr8Do0%2F6eK2bnyrywb1r%2BG%2FroeY8TesH%2BgKkMGt%2BfZS7NXmYwUobAyS0QcpQlzlxRL43aPBlflLG%2FcoRe0HS0gfneXH9BoT6AavGpxJe%2Fbghro%2FO6fOA%2FkxF%2F8mKseXEfcEmJBUCfMiuXbHmPbmDv8wm4h%2Bhmo2oETgw3cfOwwY6sAEm2kl6gCCFcifa%2FSqQpjenQ0jZJvvQn1SJLavifyVSogutMWjBZsaHq7%2BTWFjm%2B7DdGLdaMbZ%2FPW2IhcC9E6FLWei307PEufQKqxtHz%2B%2BQmOxgd2ICZOyoeHaPr8gYWRbmG%2FvrcLZmrBj3jPzryu6KoOhivcowsqhYUr5%2B3RUidJ%2B8fh9GDk%2FBV02m8iFJsnapdGQr8UfJ%2Bd45l6eSrUH8gUhGKivOmZKwdj9Z%2FI0DVw%3D%3D&Expires=1752409690", "ytTestTimeout": 1500, "prioritizeHls": false, "autoplay": false, "ytApiUrl": "https://www.youtube.com/iframe_api", "completionPercentage": 0.95, "savedVideoPosition": 0.0, "transcriptAvailableTranslationsUrl": "/courses/course-v1:MITx+15.480x+3T2021/xblock/block-v1:MITx+15.480x+3T2021+type@video+block@473a0a58f42a405586e5a8259920584c/handler/transcript/available_translations", "transcriptLanguage": "en", "transcriptTranslationUrl": "/courses/course-v1:MITx+15.480x+3T2021/xblock/block-v1:MITx+15.480x+3T2021+type@video+block@473a0a58f42a405586e5a8259920584c/handler/transcript/translation/__lang__", "saveStateEnabled": false, "duration": 105.46, "showCaptions": "true", "completionEnabled": false, "streams": "", "start": 0.0, "saveStateUrl": "/courses/course-v1:MITx+15.480x+3T2021/xblock/block-v1:MITx+15.480x+3T2021+type@video+block@473a0a58f42a405586e5a8259920584c/handler/xmodule_handler/save_user_state", "autohideHtml5": false, "sources": ["https://d2f1egay8yehza.cloudfront.net/MITx15.482x-V013500_DTH.mp4", "https://d2f1egay8yehza.cloudfront.net/MITx15.482x-V013500/MITx15.482x-V013500.m3u8"], "lmsRootURL": "https://openlearninglibrary.mit.edu", "end": 0.0, "transcriptLanguages": {"en": "English"}, "generalSpeed": 1.0, "publishCompletionUrl": "/courses/course-v1:MITx+15.480x+3T2021/xblock/block-v1:MITx+15.480x+3T2021+type@video+block@473a0a58f42a405586e5a8259920584c/handler/publish_completion"}' data-bumper-metadata='null' data-autoadvance-enabled="False" data-poster='null' tabindex="-1" > <div class="focus_grabber first"></div> <div class="tc-wrapper"> <div class="video-wrapper"> <span tabindex="0" class="spinner" aria-hidden="false" aria-label="Loading video player"></span> <span tabindex="-1" class="btn-play fa fa-youtube-play fa-2x is-hidden" aria-hidden="true" aria-label="Play video"></span> <div class="video-player-pre"></div> <div class="video-player"> <div id="473a0a58f42a405586e5a8259920584c"></div> <h4 class="hd hd-4 video-error is-hidden">No playable video sources found.</h4> <h4 class="hd hd-4 video-hls-error is-hidden"> Your browser does not support this video format. Try using a different browser. </h4> </div> <div class="video-player-post"></div> <div class="closed-captions"></div> <div class="video-controls is-hidden"> <div> <div class="vcr"><div class="vidtime">0:00 / 0:00</div></div> <div class="secondary-controls"></div> </div> </div> </div> </div> <div class="focus_grabber last"></div> </div> </div> </div> </div> </div>

<div class="xblock xblock-public_view xblock-public_view-vertical" data-runtime-class="LmsRuntime" data-block-type="vertical" data-usage-id="block-v1:MITx+15.480x+3T2021+type@vertical+block@5e57944336e8485fbef0eb2ae9749385" data-course-id="course-v1:MITx+15.480x+3T2021" data-init="VerticalStudentView" data-has-score="False" data-graded="False" data-request-token="21d032bf5fe411f0bb5812a532d12aaf" data-runtime-version="1"> <h2 class="hd hd-2 unit-title">Why Not Create “Consumer Reports”?</h2> <div class="vert-mod"> <div class="vert vert-0" data-id="block-v1:MITx+15.480x+3T2021+type@video+block@baea4429b43d4879aa4e95e2f1edf0ae"> <div class="xblock xblock-public_view xblock-public_view-video xmodule_display xmodule_VideoBlock" data-runtime-class="LmsRuntime" data-block-type="video" data-usage-id="block-v1:MITx+15.480x+3T2021+type@video+block@baea4429b43d4879aa4e95e2f1edf0ae" data-course-id="course-v1:MITx+15.480x+3T2021" data-init="XBlockToXModuleShim" data-has-score="False" data-graded="False" data-request-token="21d032bf5fe411f0bb5812a532d12aaf" data-runtime-version="1"> <script type="json/xblock-args" class="xblock-json-init-args"> {"xmodule-type": "Video"} </script> <h3 class="hd hd-2">Why Not Create “Consumer Reports”?</h3> <div id="video_baea4429b43d4879aa4e95e2f1edf0ae" class="video closed" data-metadata='{"speed": null, "ytMetadataEndpoint": "", "recordedYoutubeIsAvailable": true, "captionDataDir": null, "autoAdvance": false, "poster": "https://mitx-edx-video-meta-storage.s3.amazonaws.com/media/video-images/d505c27118ce431cb868a68bda05c11d.png?Signature=baY8b8zVyn5YOzSZ8O%2FqF7MxHkk%3D&AWSAccessKeyId=ASIA4QDFFSUR7AJWXVI4&x-amz-security-token=IQoJb3JpZ2luX2VjEP3%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEaCXVzLWVhc3QtMSJIMEYCIQDrL6n%2B6JZK2mP55A%2BuycKvWm%2Bu7QSkQfWE8Ca5X54KWwIhAL3SiAgLUuHMBLLvzN%2FZs5VmdQ3FIcWxprkcUoY%2B5V%2BoKroFCBUQBBoMODU5MjA1NjM3NDExIgwadLjPSqqzBrk%2B3QAqlwUR5uIAm4pfv2QpR97GfxL%2F%2B5Nvv2cTm%2FsbjYl11S8%2Bpn2Jj5GvOCaoCc6RrUrBezUuKFKY5sQzNBeReNVA72oTx5CKUfBeVeg%2FyjgMf43RmXtsadbPsi1LgluiwVna9Zxe%2Ft7U5Zm2UUO7oMTrr7G3ashtWD8DwPyTpVfNmRkFBPwSY%2FG3QDpnvrqm0JwTh7FBdZSM6oZR5k7vUG8MSqDd8RuL9f%2BjUspEAcTGuk6vtQqA8b0%2BtMnIlxfMWkZ2%2BlWIL2%2F2F%2FhafgEALddld3jCrJ7UIAxKTcD2B5ZI%2BzZGpzYh9cVSKHaGOdXNTVNKO4z1ViayQccZUyH1G6%2Bsx9pq3WOotc85sp5PzJfmu5WitZ4Rd31Yj0Grf7q581FvJdi7Penmyf071jQne1kLJvyf%2BtKeyQXMSViZYR%2BypAaFxzbJF61q33XvFO1wABmpGkXL14S5sU5DTyyl6AJU%2FQ1zrOzxF2cRGFuJtxUX70fsil8aNNI85kglBLZMLBiYEiA%2FQ50MNoQS9ITns4CMLEjbZPu8rRPw2DGSlPsEuOgv7PBqgsOEMiJSxQNLx8InyR5YUYKMW%2BW1bClZxoAwbmN0zb39xi8ZINq2zQ2Gj94AELxWbwNIJq2ZBfZMXD5AT8QDvMJpZj0ANQDuMkX4tNDvVkhUNRDxJgsiQoMDULNUaVsRdUUOp1yWJXjZ8yEVYWWzwLJ%2BymU5QhE%2FNWkoGr8Do0%2F6eK2bnyrywb1r%2BG%2FroeY8TesH%2BgKkMGt%2BfZS7NXmYwUobAyS0QcpQlzlxRL43aPBlflLG%2FcoRe0HS0gfneXH9BoT6AavGpxJe%2Fbghro%2FO6fOA%2FkxF%2F8mKseXEfcEmJBUCfMiuXbHmPbmDv8wm4h%2Bhmo2oETgw3cfOwwY6sAEm2kl6gCCFcifa%2FSqQpjenQ0jZJvvQn1SJLavifyVSogutMWjBZsaHq7%2BTWFjm%2B7DdGLdaMbZ%2FPW2IhcC9E6FLWei307PEufQKqxtHz%2B%2BQmOxgd2ICZOyoeHaPr8gYWRbmG%2FvrcLZmrBj3jPzryu6KoOhivcowsqhYUr5%2B3RUidJ%2B8fh9GDk%2FBV02m8iFJsnapdGQr8UfJ%2Bd45l6eSrUH8gUhGKivOmZKwdj9Z%2FI0DVw%3D%3D&Expires=1752409691", "ytTestTimeout": 1500, "prioritizeHls": false, "autoplay": false, "ytApiUrl": "https://www.youtube.com/iframe_api", "completionPercentage": 0.95, "savedVideoPosition": 0.0, "transcriptAvailableTranslationsUrl": "/courses/course-v1:MITx+15.480x+3T2021/xblock/block-v1:MITx+15.480x+3T2021+type@video+block@baea4429b43d4879aa4e95e2f1edf0ae/handler/transcript/available_translations", "transcriptLanguage": "en", "transcriptTranslationUrl": "/courses/course-v1:MITx+15.480x+3T2021/xblock/block-v1:MITx+15.480x+3T2021+type@video+block@baea4429b43d4879aa4e95e2f1edf0ae/handler/transcript/translation/__lang__", "saveStateEnabled": false, "duration": 178.58, "showCaptions": "true", "completionEnabled": false, "streams": "", "start": 0.0, "saveStateUrl": "/courses/course-v1:MITx+15.480x+3T2021/xblock/block-v1:MITx+15.480x+3T2021+type@video+block@baea4429b43d4879aa4e95e2f1edf0ae/handler/xmodule_handler/save_user_state", "autohideHtml5": false, "sources": ["https://d2f1egay8yehza.cloudfront.net/MITx15.482x-V012800_DTH.mp4", "https://d2f1egay8yehza.cloudfront.net/MITx15.482x-V012800/MITx15.482x-V012800.m3u8"], "lmsRootURL": "https://openlearninglibrary.mit.edu", "end": 0.0, "transcriptLanguages": {"en": "English"}, "generalSpeed": 1.0, "publishCompletionUrl": "/courses/course-v1:MITx+15.480x+3T2021/xblock/block-v1:MITx+15.480x+3T2021+type@video+block@baea4429b43d4879aa4e95e2f1edf0ae/handler/publish_completion"}' data-bumper-metadata='null' data-autoadvance-enabled="False" data-poster='null' tabindex="-1" > <div class="focus_grabber first"></div> <div class="tc-wrapper"> <div class="video-wrapper"> <span tabindex="0" class="spinner" aria-hidden="false" aria-label="Loading video player"></span> <span tabindex="-1" class="btn-play fa fa-youtube-play fa-2x is-hidden" aria-hidden="true" aria-label="Play video"></span> <div class="video-player-pre"></div> <div class="video-player"> <div id="baea4429b43d4879aa4e95e2f1edf0ae"></div> <h4 class="hd hd-4 video-error is-hidden">No playable video sources found.</h4> <h4 class="hd hd-4 video-hls-error is-hidden"> Your browser does not support this video format. Try using a different browser. </h4> </div> <div class="video-player-post"></div> <div class="closed-captions"></div> <div class="video-controls is-hidden"> <div> <div class="vcr"><div class="vidtime">0:00 / 0:00</div></div> <div class="secondary-controls"></div> </div> </div> </div> </div> <div class="focus_grabber last"></div> </div> </div> </div> </div> </div>

<div class="xblock xblock-public_view xblock-public_view-vertical" data-runtime-class="LmsRuntime" data-block-type="vertical" data-usage-id="block-v1:MITx+15.480x+3T2021+type@vertical+block@a80130447fc7485bb90bade02a004f03" data-course-id="course-v1:MITx+15.480x+3T2021" data-init="VerticalStudentView" data-has-score="False" data-graded="False" data-request-token="21d032bf5fe411f0bb5812a532d12aaf" data-runtime-version="1"> <h2 class="hd hd-2 unit-title">Interactive: ICER</h2> <div class="vert-mod"> <div class="vert vert-0" data-id="block-v1:MITx+15.480x+3T2021+type@html+block@5c2be7a58c7f4e519ed966048ca38d2f"> <div class="xblock xblock-public_view xblock-public_view-html xmodule_display xmodule_HtmlBlock" data-runtime-class="LmsRuntime" data-block-type="html" data-usage-id="block-v1:MITx+15.480x+3T2021+type@html+block@5c2be7a58c7f4e519ed966048ca38d2f" data-course-id="course-v1:MITx+15.480x+3T2021" data-init="XBlockToXModuleShim" data-has-score="False" data-graded="False" data-request-token="21d032bf5fe411f0bb5812a532d12aaf" data-runtime-version="1"> <script type="json/xblock-args" class="xblock-json-init-args"> {"xmodule-type": "HTMLModule"} </script> <p style="text-align: left;">The graph below shows the region (shaded green) for therapies deemed cost-effective given a particular cost-effectiveness threshold.  What happens to the cost-effectiveness of a therapy if you decrease its incremental effectiveness (measured in QALYs). What happens if you lower its incremental cost?</p> <p style="text-align: center;"><iframe title="Perpetuity" src="https://courses.edx.org/asset-v1:MITx+15.482x+1T2019+type@asset+block@Unit10_ICER.html" width="540" height="620" marginwidth="0" marginheight="0" frameborder="0" scrolling="no"> Your browser does not support IFrames. </iframe></p> </div> </div> </div> </div>

<div class="xblock xblock-public_view xblock-public_view-vertical" data-runtime-class="LmsRuntime" data-block-type="vertical" data-usage-id="block-v1:MITx+15.480x+3T2021+type@vertical+block@1dff71cff1d9457382159f1d4f51f7ee" data-course-id="course-v1:MITx+15.480x+3T2021" data-init="VerticalStudentView" data-has-score="False" data-graded="False" data-request-token="21d032bf5fe411f0bb5812a532d12aaf" data-runtime-version="1"> <h2 class="hd hd-2 unit-title">Exercise: ICER</h2> <div class="vert-mod"> <div class="vert vert-0" data-id="block-v1:MITx+15.480x+3T2021+type@problem+block@2e3144cfe03b47169f0c27ba9b4c3898"> <div class="xblock xblock-public_view xblock-public_view-problem xmodule_display xmodule_ProblemBlock" data-runtime-class="LmsRuntime" data-block-type="problem" data-usage-id="block-v1:MITx+15.480x+3T2021+type@problem+block@2e3144cfe03b47169f0c27ba9b4c3898" data-course-id="course-v1:MITx+15.480x+3T2021" data-init="XBlockToXModuleShim" data-has-score="True" data-graded="False" data-request-token="21d032bf5fe411f0bb5812a532d12aaf" data-runtime-version="1"> <script type="json/xblock-args" class="xblock-json-init-args"> {"xmodule-type": "Problem"} </script> <div id="problem_2e3144cfe03b47169f0c27ba9b4c3898" class="problems-wrapper" role="group" aria-labelledby="2e3144cfe03b47169f0c27ba9b4c3898-problem-title" data-problem-id="block-v1:MITx+15.480x+3T2021+type@problem+block@2e3144cfe03b47169f0c27ba9b4c3898" data-url="/courses/course-v1:MITx+15.480x+3T2021/xblock/block-v1:MITx+15.480x+3T2021+type@problem+block@2e3144cfe03b47169f0c27ba9b4c3898/handler/xmodule_handler" data-problem-score="0" data-problem-total-possible="1" data-attempts-used="0" data-content=" <h3 class="hd hd-3 problem-header" id="2e3144cfe03b47169f0c27ba9b4c3898-problem-title" aria-describedby="block-v1:MITx+15.480x+3T2021+type@problem+block@2e3144cfe03b47169f0c27ba9b4c3898-problem-progress" tabindex="-1"> Exercise: ICER </h3> <div class="problem-progress" id="block-v1:MITx+15.480x+3T2021+type@problem+block@2e3144cfe03b47169f0c27ba9b4c3898-problem-progress"></div> <div class="problem"> <div> <p>Suppose that the standard treatment for metastatic breast cancer costs $100,000, and provides patients an additional 2 quality-adjusted life-years (QALYs), on average. A more effective treatment is discovered that provides patients 2.8 QALYs, but costs $200,000. If the ICER threshold for deciding whether or not to fund a therapy is $60,000 per QALY, then will this new treatment be deemed cost-effective and funded?</p> <p> <div class="wrapper-problem-response" tabindex="-1" aria-label="Question 1" role="group"><div class="choicegroup capa_inputtype" id="inputtype_2e3144cfe03b47169f0c27ba9b4c3898_2_1"> <fieldset aria-describedby="status_2e3144cfe03b47169f0c27ba9b4c3898_2_1"> <div class="field"> <input type="radio" name="input_2e3144cfe03b47169f0c27ba9b4c3898_2_1" id="input_2e3144cfe03b47169f0c27ba9b4c3898_2_1_choice_0" class="field-input input-radio" value="choice_0"/><label id="2e3144cfe03b47169f0c27ba9b4c3898_2_1-choice_0-label" for="input_2e3144cfe03b47169f0c27ba9b4c3898_2_1_choice_0" class="response-label field-label label-inline" aria-describedby="status_2e3144cfe03b47169f0c27ba9b4c3898_2_1"> Yes </label> </div> <div class="field"> <input type="radio" name="input_2e3144cfe03b47169f0c27ba9b4c3898_2_1" id="input_2e3144cfe03b47169f0c27ba9b4c3898_2_1_choice_1" class="field-input input-radio" value="choice_1"/><label id="2e3144cfe03b47169f0c27ba9b4c3898_2_1-choice_1-label" for="input_2e3144cfe03b47169f0c27ba9b4c3898_2_1_choice_1" class="response-label field-label label-inline" aria-describedby="status_2e3144cfe03b47169f0c27ba9b4c3898_2_1"> No </label> </div> <span id="answer_2e3144cfe03b47169f0c27ba9b4c3898_2_1"/> </fieldset> <div class="indicator-container"> <span class="status unanswered" id="status_2e3144cfe03b47169f0c27ba9b4c3898_2_1" data-tooltip="Not yet answered."> <span class="sr">unanswered</span><span class="status-icon" aria-hidden="true"/> </span> </div> </div></div> </p> <div class="solution-span"> <span id="solution_2e3144cfe03b47169f0c27ba9b4c3898_solution_1"/> </div></div> <div class="action"> <input type="hidden" name="problem_id" value="Exercise: ICER" /> <div class="submit-attempt-container"> <button type="button" class="submit btn-brand" data-submitting="Submitting" data-value="Submit" data-should-enable-submit-button="True" aria-describedby="submission_feedback_2e3144cfe03b47169f0c27ba9b4c3898" > <span class="submit-label">Submit</span> </button> <div class="submission-feedback" id="submission_feedback_2e3144cfe03b47169f0c27ba9b4c3898"> <span class="sr">Some problems have options such as save, reset, hints, or show answer. These options follow the Submit button.</span> </div> </div> <div class="problem-action-buttons-wrapper"> <span class="problem-action-button-wrapper"> <button type="button" class="show problem-action-btn btn-default btn-small" aria-describedby="2e3144cfe03b47169f0c27ba9b4c3898-problem-title"><span class="icon fa fa-info-circle" aria-hidden="true"></span><span class="show-label">Show Answer</span></button> </span> </div> </div> <div class="notification warning notification-gentle-alert is-hidden" tabindex="-1"> <span class="icon fa fa-exclamation-circle" aria-hidden="true"></span> <span class="notification-message" aria-describedby="2e3144cfe03b47169f0c27ba9b4c3898-problem-title"> </span> <div class="notification-btn-wrapper"> <button type="button" class="btn btn-default btn-small notification-btn review-btn sr">Review</button> </div> </div> <div class="notification warning notification-save is-hidden" tabindex="-1"> <span class="icon fa fa-save" aria-hidden="true"></span> <span class="notification-message" aria-describedby="2e3144cfe03b47169f0c27ba9b4c3898-problem-title">None </span> <div class="notification-btn-wrapper"> <button type="button" class="btn btn-default btn-small notification-btn review-btn sr">Review</button> </div> </div> <div class="notification general notification-show-answer is-hidden" tabindex="-1"> <span class="icon fa fa-info-circle" aria-hidden="true"></span> <span class="notification-message" aria-describedby="2e3144cfe03b47169f0c27ba9b4c3898-problem-title">Answers are displayed within the problem </span> <div class="notification-btn-wrapper"> <button type="button" class="btn btn-default btn-small notification-btn review-btn sr">Review</button> </div> </div> </div> " data-graded="False"> <p class="loading-spinner"> <i class="fa fa-spinner fa-pulse fa-2x fa-fw"></i> <span class="sr">Loading…</span> </p> </div> </div> </div> </div> </div>

<div class="xblock xblock-public_view xblock-public_view-vertical" data-runtime-class="LmsRuntime" data-block-type="vertical" data-usage-id="block-v1:MITx+15.480x+3T2021+type@vertical+block@f9aa5f40528f4f1ebce412e7bcc35d13" data-course-id="course-v1:MITx+15.480x+3T2021" data-init="VerticalStudentView" data-has-score="False" data-graded="False" data-request-token="21d032bf5fe411f0bb5812a532d12aaf" data-runtime-version="1"> <h2 class="hd hd-2 unit-title">UK: NICE</h2> <div class="vert-mod"> <div class="vert vert-0" data-id="block-v1:MITx+15.480x+3T2021+type@video+block@c85d75109fb245e19dabc8bc69bd2bdd"> <div class="xblock xblock-public_view xblock-public_view-video xmodule_display xmodule_VideoBlock" data-runtime-class="LmsRuntime" data-block-type="video" data-usage-id="block-v1:MITx+15.480x+3T2021+type@video+block@c85d75109fb245e19dabc8bc69bd2bdd" data-course-id="course-v1:MITx+15.480x+3T2021" data-init="XBlockToXModuleShim" data-has-score="False" data-graded="False" data-request-token="21d032bf5fe411f0bb5812a532d12aaf" data-runtime-version="1"> <script type="json/xblock-args" class="xblock-json-init-args"> {"xmodule-type": "Video"} </script> <h3 class="hd hd-2">UK: NICE</h3> <div id="video_c85d75109fb245e19dabc8bc69bd2bdd" class="video closed" data-metadata='{"speed": null, "ytMetadataEndpoint": "", "recordedYoutubeIsAvailable": true, "captionDataDir": null, "autoAdvance": false, "poster": null, "ytTestTimeout": 1500, "prioritizeHls": false, "autoplay": false, "ytApiUrl": "https://www.youtube.com/iframe_api", "completionPercentage": 0.95, "savedVideoPosition": 0.0, "transcriptAvailableTranslationsUrl": "/courses/course-v1:MITx+15.480x+3T2021/xblock/block-v1:MITx+15.480x+3T2021+type@video+block@c85d75109fb245e19dabc8bc69bd2bdd/handler/transcript/available_translations", "transcriptLanguage": "en", "transcriptTranslationUrl": "/courses/course-v1:MITx+15.480x+3T2021/xblock/block-v1:MITx+15.480x+3T2021+type@video+block@c85d75109fb245e19dabc8bc69bd2bdd/handler/transcript/translation/__lang__", "saveStateEnabled": false, "duration": 681.96, "showCaptions": "true", "completionEnabled": false, "streams": "", "start": 0.0, "saveStateUrl": "/courses/course-v1:MITx+15.480x+3T2021/xblock/block-v1:MITx+15.480x+3T2021+type@video+block@c85d75109fb245e19dabc8bc69bd2bdd/handler/xmodule_handler/save_user_state", "autohideHtml5": false, "sources": ["https://d2f1egay8yehza.cloudfront.net/MITx15.482x-V014000_DTH.mp4", "https://d2f1egay8yehza.cloudfront.net/MITx15.482x-V014000/MITx15.482x-V014000.m3u8"], "lmsRootURL": "https://openlearninglibrary.mit.edu", "end": 0.0, "transcriptLanguages": {"en": "English"}, "generalSpeed": 1.0, "publishCompletionUrl": "/courses/course-v1:MITx+15.480x+3T2021/xblock/block-v1:MITx+15.480x+3T2021+type@video+block@c85d75109fb245e19dabc8bc69bd2bdd/handler/publish_completion"}' data-bumper-metadata='null' data-autoadvance-enabled="False" data-poster='null' tabindex="-1" > <div class="focus_grabber first"></div> <div class="tc-wrapper"> <div class="video-wrapper"> <span tabindex="0" class="spinner" aria-hidden="false" aria-label="Loading video player"></span> <span tabindex="-1" class="btn-play fa fa-youtube-play fa-2x is-hidden" aria-hidden="true" aria-label="Play video"></span> <div class="video-player-pre"></div> <div class="video-player"> <div id="c85d75109fb245e19dabc8bc69bd2bdd"></div> <h4 class="hd hd-4 video-error is-hidden">No playable video sources found.</h4> <h4 class="hd hd-4 video-hls-error is-hidden"> Your browser does not support this video format. Try using a different browser. </h4> </div> <div class="video-player-post"></div> <div class="closed-captions"></div> <div class="video-controls is-hidden"> <div> <div class="vcr"><div class="vidtime">0:00 / 0:00</div></div> <div class="secondary-controls"></div> </div> </div> </div> </div> <div class="focus_grabber last"></div> </div> </div> </div> </div> </div>

<div class="xblock xblock-public_view xblock-public_view-vertical" data-runtime-class="LmsRuntime" data-block-type="vertical" data-usage-id="block-v1:MITx+15.480x+3T2021+type@vertical+block@dac4b5ce7cff46539a7b33115b674ac5" data-course-id="course-v1:MITx+15.480x+3T2021" data-init="VerticalStudentView" data-has-score="False" data-graded="False" data-request-token="21d032bf5fe411f0bb5812a532d12aaf" data-runtime-version="1"> <h2 class="hd hd-2 unit-title">We Need a New Approach</h2> <div class="vert-mod"> <div class="vert vert-0" data-id="block-v1:MITx+15.480x+3T2021+type@video+block@c38cce922ea8494bb129a6520510b04c"> <div class="xblock xblock-public_view xblock-public_view-video xmodule_display xmodule_VideoBlock" data-runtime-class="LmsRuntime" data-block-type="video" data-usage-id="block-v1:MITx+15.480x+3T2021+type@video+block@c38cce922ea8494bb129a6520510b04c" data-course-id="course-v1:MITx+15.480x+3T2021" data-init="XBlockToXModuleShim" data-has-score="False" data-graded="False" data-request-token="21d032bf5fe411f0bb5812a532d12aaf" data-runtime-version="1"> <script type="json/xblock-args" class="xblock-json-init-args"> {"xmodule-type": "Video"} </script> <h3 class="hd hd-2">We Need a New Approach</h3> <div id="video_c38cce922ea8494bb129a6520510b04c" class="video closed" data-metadata='{"speed": null, "ytMetadataEndpoint": "", "recordedYoutubeIsAvailable": true, "captionDataDir": null, "autoAdvance": false, "poster": "https://mitx-edx-video-meta-storage.s3.amazonaws.com/media/video-images/d1d4c49186444f509ad6c4416df3d6e4.png?Signature=5UeALkPTaXtDkT6%2Fc4iy55hkCLk%3D&AWSAccessKeyId=ASIA4QDFFSUR7AJWXVI4&x-amz-security-token=IQoJb3JpZ2luX2VjEP3%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEaCXVzLWVhc3QtMSJIMEYCIQDrL6n%2B6JZK2mP55A%2BuycKvWm%2Bu7QSkQfWE8Ca5X54KWwIhAL3SiAgLUuHMBLLvzN%2FZs5VmdQ3FIcWxprkcUoY%2B5V%2BoKroFCBUQBBoMODU5MjA1NjM3NDExIgwadLjPSqqzBrk%2B3QAqlwUR5uIAm4pfv2QpR97GfxL%2F%2B5Nvv2cTm%2FsbjYl11S8%2Bpn2Jj5GvOCaoCc6RrUrBezUuKFKY5sQzNBeReNVA72oTx5CKUfBeVeg%2FyjgMf43RmXtsadbPsi1LgluiwVna9Zxe%2Ft7U5Zm2UUO7oMTrr7G3ashtWD8DwPyTpVfNmRkFBPwSY%2FG3QDpnvrqm0JwTh7FBdZSM6oZR5k7vUG8MSqDd8RuL9f%2BjUspEAcTGuk6vtQqA8b0%2BtMnIlxfMWkZ2%2BlWIL2%2F2F%2FhafgEALddld3jCrJ7UIAxKTcD2B5ZI%2BzZGpzYh9cVSKHaGOdXNTVNKO4z1ViayQccZUyH1G6%2Bsx9pq3WOotc85sp5PzJfmu5WitZ4Rd31Yj0Grf7q581FvJdi7Penmyf071jQne1kLJvyf%2BtKeyQXMSViZYR%2BypAaFxzbJF61q33XvFO1wABmpGkXL14S5sU5DTyyl6AJU%2FQ1zrOzxF2cRGFuJtxUX70fsil8aNNI85kglBLZMLBiYEiA%2FQ50MNoQS9ITns4CMLEjbZPu8rRPw2DGSlPsEuOgv7PBqgsOEMiJSxQNLx8InyR5YUYKMW%2BW1bClZxoAwbmN0zb39xi8ZINq2zQ2Gj94AELxWbwNIJq2ZBfZMXD5AT8QDvMJpZj0ANQDuMkX4tNDvVkhUNRDxJgsiQoMDULNUaVsRdUUOp1yWJXjZ8yEVYWWzwLJ%2BymU5QhE%2FNWkoGr8Do0%2F6eK2bnyrywb1r%2BG%2FroeY8TesH%2BgKkMGt%2BfZS7NXmYwUobAyS0QcpQlzlxRL43aPBlflLG%2FcoRe0HS0gfneXH9BoT6AavGpxJe%2Fbghro%2FO6fOA%2FkxF%2F8mKseXEfcEmJBUCfMiuXbHmPbmDv8wm4h%2Bhmo2oETgw3cfOwwY6sAEm2kl6gCCFcifa%2FSqQpjenQ0jZJvvQn1SJLavifyVSogutMWjBZsaHq7%2BTWFjm%2B7DdGLdaMbZ%2FPW2IhcC9E6FLWei307PEufQKqxtHz%2B%2BQmOxgd2ICZOyoeHaPr8gYWRbmG%2FvrcLZmrBj3jPzryu6KoOhivcowsqhYUr5%2B3RUidJ%2B8fh9GDk%2FBV02m8iFJsnapdGQr8UfJ%2Bd45l6eSrUH8gUhGKivOmZKwdj9Z%2FI0DVw%3D%3D&Expires=1752409691", "ytTestTimeout": 1500, "prioritizeHls": false, "autoplay": false, "ytApiUrl": "https://www.youtube.com/iframe_api", "completionPercentage": 0.95, "savedVideoPosition": 0.0, "transcriptAvailableTranslationsUrl": "/courses/course-v1:MITx+15.480x+3T2021/xblock/block-v1:MITx+15.480x+3T2021+type@video+block@c38cce922ea8494bb129a6520510b04c/handler/transcript/available_translations", "transcriptLanguage": "en", "transcriptTranslationUrl": "/courses/course-v1:MITx+15.480x+3T2021/xblock/block-v1:MITx+15.480x+3T2021+type@video+block@c38cce922ea8494bb129a6520510b04c/handler/transcript/translation/__lang__", "saveStateEnabled": false, "duration": 569.04, "showCaptions": "true", "completionEnabled": false, "streams": "", "start": 0.0, "saveStateUrl": "/courses/course-v1:MITx+15.480x+3T2021/xblock/block-v1:MITx+15.480x+3T2021+type@video+block@c38cce922ea8494bb129a6520510b04c/handler/xmodule_handler/save_user_state", "autohideHtml5": false, "sources": ["https://d2f1egay8yehza.cloudfront.net/MITx15.482x-V013700_DTH.mp4", "https://d2f1egay8yehza.cloudfront.net/MITx15.482x-V013700/MITx15.482x-V013700.m3u8"], "lmsRootURL": "https://openlearninglibrary.mit.edu", "end": 0.0, "transcriptLanguages": {"en": "English"}, "generalSpeed": 1.0, "publishCompletionUrl": "/courses/course-v1:MITx+15.480x+3T2021/xblock/block-v1:MITx+15.480x+3T2021+type@video+block@c38cce922ea8494bb129a6520510b04c/handler/publish_completion"}' data-bumper-metadata='null' data-autoadvance-enabled="False" data-poster='null' tabindex="-1" > <div class="focus_grabber first"></div> <div class="tc-wrapper"> <div class="video-wrapper"> <span tabindex="0" class="spinner" aria-hidden="false" aria-label="Loading video player"></span> <span tabindex="-1" class="btn-play fa fa-youtube-play fa-2x is-hidden" aria-hidden="true" aria-label="Play video"></span> <div class="video-player-pre"></div> <div class="video-player"> <div id="c38cce922ea8494bb129a6520510b04c"></div> <h4 class="hd hd-4 video-error is-hidden">No playable video sources found.</h4> <h4 class="hd hd-4 video-hls-error is-hidden"> Your browser does not support this video format. Try using a different browser. </h4> </div> <div class="video-player-post"></div> <div class="closed-captions"></div> <div class="video-controls is-hidden"> <div> <div class="vcr"><div class="vidtime">0:00 / 0:00</div></div> <div class="secondary-controls"></div> </div> </div> </div> </div> <div class="focus_grabber last"></div> </div> </div> </div> </div> </div>