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<h2 class="hd hd-2 unit-title">Reference Summary</h2>
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<h3> <b> Anatomy of an amino acid polymer </b> </h3>
<img src='/assets/courseware/v1/50fcf594165889e2c77014ec9b97cf54/asset-v1:OCW+Pre-7.01+1T2020+type@asset+block/f1.png'>
<p> The diagram above shows the synthesis of a dipeptide from two amino acid monomers. <br /> The alpha-carbons have been circled in orange. <br/> The peptide bond that forms upon synthesis is circled in blue. <br /> </p>
<p> The polypeptide is polymerized from the N end to the C end. The amino acid at the N end has a free NH<sub>2</sub> group and the amino acid at the C end has a free COOH group. </p>
<h3> <b> Nomenclature </b> </h3>
<p> Proteins are written with three or one letter amino acid code from N to C.
<br /> <em><b> ALWAYS write N and C on each protein! </b></em>
<p> For example: </p>
<img src='/assets/courseware/v1/7f88ace8f35cf7ab242c78a809cbcea9/asset-v1:OCW+Pre-7.01+1T2020+type@asset+block/f3.png' >
<p> OR, from the diagram above:</p>
<img src='/assets/courseware/v1/77463e41217ce36ae0e2c0e4e396f4b5/asset-v1:OCW+Pre-7.01+1T2020+type@asset+block/f2.png'>
<br /><br />
<h3> <b> Polarity of Synthesis </b> </h3>
<p> A polypeptide chain is synthesized from N to C. Therefore, the –C end is the growing end (for addition of next amino acid).
<br /><br /> <b> Amino acid order = INFORMATION <br /> Polarity = N and C ends show first to last amino acid added </b></p>
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<h2 class="hd hd-2 unit-title">Exercise 1 (Labeling and Building Proteins)</h2>
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<p>Which of the following correctly demonstrates how to label the N end of the protein below?<br/>Select the best answer.</p>
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<b> C-Ala-Tyr-Asn-Val </b>
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Question 3
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<p>Click on the image below to to place the circle at the part of the polymer where the incoming Trp amino acid will be added.</p>
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